Discover CircRes

This month on Episode 89 of Discover CircRes, host Cindy St. Hilaire highlights articles featured in the September 25th and October 9th issues of Circulation Research. This Episode also features a discussion with Dr Abhinav Diwan, Dr Xumin Guan, and Dr David Rawnsley about their study, "Mitophagy Facilitates Cytosolic Proteostasis to Preserve Cardiac Function."   Article highlights: Wang, et al. Chronic Colitis and Cardiac Hypertrophy Li, et al. FPR1 Drives Angiogenesis in PAOD Gao, et al. CD8+ T-Cells Negatively Regulate Notch in VSMCs Dapergola, et al. Latent CMV Infection Impacts Post-MI Repair

This month on Episode 88 of Discover CircRes, host Cindy St. Hilaire highlights articles featured in the August 28th and September 11th issues of Circulation Research. This Episode also features a discussion with Dr Klaus Ley about his study, "Increased Autoreactive CD8+ T Cells to Apolipoprotein B Epitopes in Patients with Severe Coronary Artery Disease."   Article highlights: Wang, et al. Methylmalonate Drives Diabetic Heart Damage Zheng, et al. TLS and CXCL13 Axis in Intracranial Aneurysms Zhou, et al. A Glyco-Epigenetic Driver of Heart Failure Wang, et al Formononetin as an ERRα Agonist Alleviates AIC

This month on Episode 87 of Discover CircRes, host Cindy St. Hilaire highlights articles featured in the July 31st and August 14th issues of Circulation Research. This Episode also features a discussion with Drs Jonathan Kirk, Laura Sherer, and Abigail Nagle about their study, "Contractility Drives Cardiomyocyte Maturation and the Response to Nanopatterns."   Article highlights: Zhang, et al. Mitochondrial STING Reprograms Glycolysis Daou, et al. TFEB Antagonizes Pathological Cardiac Hypertrophy Crepin, et al. Macrophage Subsets Contribute to Atrial Remodeling Okamura, et al. Stochastic Resonance Prevents Sinus Arrest

This month on Episode 86 of Discover CircRes, host Cindy St. Hilaire highlights articles featured in the July 6 and July 17th issues of Circulation Research. This Episode also features a discussion with BCVS Outstanding Early Career Investigator Award Finalists, Drs Noor Momin, Shibali Das, and Ivan Menendez-Montes.   Article highlights: Kotla, et al. LATS1/2-CD38-SUOX Axis Drives Intraplaque Thrombosis Lin, et al. ATAD3A Gates Mito-Lysosome Contacts in AAD Wang, et al. Monocyte Dll4 Induces Systemic Inflammation Chattopadhyay, et al. S100A8/A9 Aggravate Atherosclerosis

This month on Episode 85 of Discover CircRes, host Cindy St. Hilaire highlights articles featured in the May 22nd, June 5th and June 19th issues of Circulation Research. This Episode also features a discussion with Professor Katrin Schäfer, Dr Rajinikanth Gogiraju, and Dr Beichen Sun, about their study, Chronic Erythrocyte NO Production Accelerates Atherosclerosis by Increasing SMC De Novo Lipogenesis.   Article highlights: Larcher, et al. Cardiac Fibroblast Heterogeneity and Disease Huang, et al. Vascular Endothelial NOX1 Drives Obesity Atici, et al. Role of Sirtuin-1 in Murine Vasculitis Compendium on Lipoproteins and Cardiovascular Disease

This month on Episode 84 of Discover CircRes, host Cindy St. Hilaire highlights articles featured in the April 24th and May 8th issue of Circulation Research. This Episode also features a discussion with Dr Mete Civelek and Dr Noah Perry about their study, Female-Biased Vascular Smooth Muscle Cell Gene Regulatory Networks Predict MYH9 as a Key Regulator of Fibrous Plaque Phenotype.   Article highlights: Westhoff, et al. PTEN and PIP3 in AngII-Induced Cardiac Pathology Witmer, et al. Novel Mode of SCN5A-Mitochondrial Crosstalk Ghiringhelli, et al. Light-Controllable Humanized Bioengineered Atria Wang, et al. Exercise-Induced Cardiomyocyte EVs Deliver EPPIR

This month on Episode 83 of Discover CircRes, host Cindy St. Hilaire highlights articles featured in the March 27th and April 10th issue of Circulation Research. This Episode also features a discussion with Dr Martin Schwartz and Dr Hanqiang Deng about their study, FOXO1 Integrates Endothelial Hemodynamic, Inflammatory, and Metabolic Pathways in Atherosclerosis.   Article highlights: Tadokoro, et al. CRISPR Base Editing of PKCα Rescues Heart Failure Joki, et al. PTH Affects Right Heart Hemodynamics Compendium on Migration of Mitochondria Beyond Cell Boundary

This month on Episode 82 of Discover CircRes, host Cindy St. Hilaire highlights articles featured in the February 27th and March 13th issue of Circulation Research. This Episode also features a discussion with Dr John Hall and Dr Ana Omoto from the University of Mississippi Medical Center about their study, Leptin Activates Brain-BAT-Heart Crosstalk to Promote Cardiac Protection.   Article highlights: Sakkers, et al. Atherosclerotic Fibrous Plaques in Women Ruberto, et al. Mitochondrial Biogenesis and Heart Regeneration Simon-Chica, et al. Non-Myocytes Modulate Atrial Fibrillation Dynamics Zhao, et al. USP10 Inhibits cGAS-STING via MTX2

This month on Episode 81 of Discover CircRes, host Cindy St. Hilaire highlights articles featured in the January 30th and February 13th issue of Circulation Research. This Episode also features a discussion with Dr Claudia Goettsch and Nicolas Hense, about their study, 1-Phosphatidylinositol 3-Phosphate 5-Kinase Inhibition by Apilimod Promotes an Adipocyte-like Vascular Smooth Muscle Cell Phenotype and Prevents Arterial Calcification.   Article highlights: Hu, et al. CircZBTB44 Inhibits Calcific Aortic Valve Disease Schemelei, et al. Olfr2 Aggravates AAA Formation Zhang, et al. Neratinib Protects Against Atherosclerosis Sun, et al. CD34+ Cells in Transplants

This month on Episode 80 of Discover CircRes, host Cindy St. Hilaire highlights articles featured in the January 2nd and January 16th issue of Circulation Research. This Episode also features a discussion with Dr Colin Evans and Dr You-Yang Zhao about their study, The Unexpected Protective Role of Thrombosis in Lung Injury via Endothelial ALOX15.   Article highlights: Viskadourou, et al. Endothelial REST in Atherosclerosis Torre, et al. Silencing the Chronotropic Heart Rate Response Chen, et al. Histone Lactylation and Cardiac Hypertrophy Vázquez-Reyes, et al. Diurnal Neutrophil Function Drives Stroke Outcome