What is the Large-Scale Structure of the Universe?

Contribute what you can to help us continue exploring the world's deepest questions without the need for paywalls.   Two big ideas in biology: the evolution of species via mutation, fitness and natural selection; and the embryological development of individuals, from fertilized egg to whole organisms. How do these two big ideas—“Evo-Dev,” as it’s called—relate? What novel ideas emerge?   Featuring interviews with Denis Noble, Richard Dawkins, Alexander Rosenberg, Philip Kitcher, Alan C. Love, and John Dupré.

James Hughes Ph.D. is the Executive Director of the Institute for Ethics and Emerging Technologies, and a bioethicist and sociologist who serves as the Associate Provost for Institutional Research, Assessment and Planning for the University of Massachusetts Boston. He holds a doctorate in sociology from the University of Chicago, where he also taught bioethics at the MacLean Center for Clinical Medical Ethics. Dr. Hughes is author of Citizen Cyborg and co-editor of Surviving the Machine Age.   Watch all of our CTT Chats here.   This Chat was made possible by MindFest 2025: "Sentience, Autonomy, and the Future of Human-AI Interaction", a two-day event presented by the Center for the Future Mind. To learn more about groundbreaking innovation in AI, neuroscience, and the study of consciousness, visit the Center for the Future Mind, view MindFest videos, and subscribe to their newsletter, visit their website.

Make a donation to Closer To Truth to help us continue exploring the world's deepest questions without the need for paywalls.   While evolution is how life on earth came to be, where does the evolution occur? At what level of the hierarchy of life—from genes to individuals to groups to species—does evolution work its selection magic? Is it multilevel?   Featuring interviews with Richard Dawkins, Lisa Lloyd, Peter Godfrey-Smith, Paul Griffiths, Elliott Sober, and Samir Okasha.

Make a donation to Closer To Truth to help us continue exploring the world's deepest questions without the need for paywalls.   How will AI-generated deepfakes reshape truth, trust, and society? Can AI someday merge with human consciousness? Futurist Zoltan Istvan explores the disruptive power of synthetic media—from political deception to personal identity—and what it means for the future of ethics, law, and reality itself.   Zoltan Istvan Gyurko, professionally known as Zoltan Istvan, is an American transhumanist, journalist, entrepreneur, political candidate, and futurist.

Make a donation to Closer To Truth to help us continue exploring the world's deepest questions without the need for paywalls: https://shorturl.at/OnyRq   Explore evolution—its scope and depth. How did life on earth come to be as it is, and how did humans come to be as we are? What are the deep principles driving evolution? What are evolution’s challenges and open questions?   Featuring interviews with Elliott Sober, Richard Dawkins, Samir Okasha, John Dupré, Denis Noble, and Michael Ruse.   Episode 1, Season 27

Make a donation to Closer To Truth to help us continue exploring the world's deepest questions without the need for paywalls.   Chris French discusses his latest book, The Science of Weird Shit, where he convincingly debunks ESP, communicating with the dead, and alien abduction claims, among other phenomena. All the while, however, French maintains that our belief in such phenomena is neither ridiculous nor trivial; if anything, such claims can tell us a great deal about the human mind if we pay them the attention they are due.   Chris French is Emeritus Professor and Head of the Anomalistic Psychology Research Unit in the Psychology Department at Goldsmiths, University of London. He is a Fellow of the British Psychological Society and of the Committee for Skeptical Inquiry and a Patron of Humanists UK. He is the coauthor of Anomalistic Psychology: Exploring Paranormal Belief and Experience.

Make a donation to Closer To Truth to help us continue exploring the world's deepest questions without the need for paywalls.   What could life be as we don’t know it? Three transitions in astrobiology. Non-life to life. Life to intelligent life. Intelligent life to technological civilization. For alien life, would Darwinian evolution hold? Fermi’s Paradox is profound: with at least 10 22 planets in the known universe, we find no evidence of alien life, anywhere, much less alien intelligence. Is there a great filter?   Featuring interviews with Carol Cleland, Richard Dawkins, Rachell Powell, Massimo Pigliucci, and Helen De Cruz.

Jonathan Schooler is an American psychologist and Distinguished Professor of Psychological and Brain Sciences at the University of California, Santa Barbara, who researches various topics that intersect aspects of both cognitive psychology and philosophy such as: Belief in free will, meta-awareness, mindfulness, mind-Wandering, memory, creativity, and emotion. Schooler is also known for his sometimes controversial research on topics such as Anomalous Cognition and the decline effect.   This interview was made possible by MindFest 2025: "Sentience, Autonomy, and the Future of Human-AI Interaction", a two-day event led by Dr. Susan Schneider and the Center for the Future Mind at Florida Atlantic University. To learn more about groundbreaking innovation in AI, neuroscience, and the study of consciousness, visit the Center for the Future Mind website and subscribe to their newsletter.

Can superintelligent AI destroy humanity—or will it collapse under its own philosophical doubts? Professor Joseph Corabi, Chair of Philosophy at Saint Joseph’s University, joins Robert Lawrence Kuhn at MindFest 2025 to explore the limits of artificial intelligence, consciousness, and the metaphysics of mind.   Drawing from his presentation, "A Collapsing Superintelligent AI?", Corabi argues that future AI—however advanced—may become paralyzed by skeptical challenges that human minds navigate through evolved psychology. Could superintelligence be undone by its inability to resolve deep epistemological puzzles?   Topics discussed include: Can AI ever be truly conscious? Is virtual immortality through mind uploading possible? Does transhumanism mark the future of humanity? Can theology and Jesuit philosophy shed light on AI, soul, and afterlife? Is there a logical justification for hell? Closer To Truth, hosted by Robert Lawrence Kuhn, presents the world’s greatest thinkers exploring humanity’s deepest questions. Discover fundamental issues of existence. Engage new and diverse ways of thinking. Appreciate intense debates. Share your own opinions. Seek your own answers.

Make a donation to Closer To Truth to help us continue exploring the world's deepest questions without the need for paywalls: https://shorturl.at/OnyRq   How do Buddhism, Chinese traditions, and Hinduism address the ultimate essence of all things, the ground of being? What are transcendence, oneness, interconnectivity, ineffability? Compare Dao in Daoism to Brahman in Hinduism. Compare Wu in Daoism with Emptiness in Buddhism. Does God fit in?   Featuring interviews with Swami Sarvapriyananda, Swami Medhananda, Jay Garfield, Franklin Perkins, and Tao Jiang.   Explore all videos on Eastern Traditions here.