Think BIG Bodybuilding podcast

Drugs n Stuff 320 Why Steroid Cycles Stop Working (And How to Keep Growing) + PED QA

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Why do steroids stop producing the same gains over time? In this episode of Drugs N Stuff, Scott McNally and Dave Crosland explain why simply running more drugs for longer eventually leads to diminishing returns—and how experienced bodybuilders structure long growth phases to keep making progress. Plus, we answer your questions on testosterone isocaproate, DHB, Dutasteride, Retatrutide, NAD+, P-21, sauna use, TRT injection frequency and much more.

⏱ TIMESTAMPS

0:00 Why Steroids Eventually Stop Working

1:00 Support Our Sponsors

3:45 How to Plan a 12-Month Growth Phase

13:40 Start Low, Build Slowly & Extend Your Cycle

20:30 Testosterone Isocaproate Half-Life Explained

24:10 Can You Re-Sensitize Yourself to Stimulants?

29:40 Scott's Experience with P-21

31:40 Selank: Scott's Honest Experience

32:50 Low-Dose Testosterone + DHB for a Specific Look

37:00 Sauna Benefits While Using PEDs

41:00 Can Retatrutide Reduce Addiction?

45:00 NAD+ Benefits & Can You Overdo Mitochondria?

48:45 Why Some Lifters Are Leaving Daily TRT Injections

49:45 Does Dutasteride Protect Against Dianabol Hair Loss?

51:50 Why Hydrochlorothiazide Is NOT Potassium Sparing

54:30 LSD as a Treatment for Depression

56:00 Uncle Dave's Wisdom

1:04:00 We Need to Buy Dave a Horn

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