Voyageur Pharmaceuticals begins human testing for advanced Barium contrast products

Caledonia Mining Corporation PLC (AIM:CMCL, NYSE-A:CMCL) chief executive Mark Learmonth talked with Proactive's Stephen Gunnion about the company's 2024 performance and 2025 plans. Despite challenges mid-year, including a fall of ground in a high-grade area, the company achieved strong fourth-quarter results, producing 76,600 ounces of gold—within its guidance range. Learmonth highlighted that December's robust production set up 2025 for a positive start, with a record stockpile of 8,000 tonnes of ore. Looking ahead, Caledonia's $35 million capital expenditure program for 2025 focuses on modernisation and strengthening the Blanket Mine’s operations, with investments in safety, ventilation, and IT systems. The company is also advancing its Bilboes feasibility study, expected in Q1 2025, and expanding exploration efforts at Motapa. Learmonth noted that the sale of the solar project is expected to be completed by the end of January 2025, providing a significant cash inflow. “This investment reflects our commitment to building a stronger, more sustainable business,” he said. For more insights and updates, visit Proactive's YouTube channel. Don’t forget to like the video, subscribe to the channel, and enable notifications for future content. #CaledoniaMining #GoldMining #BlanketMine #MiningUpdates #MarkLearmonth #2025Plans #GoldProduction #MiningInvestment #SustainableMining #ProactiveInvestors#ProactiveInvestors#invest #investing #investment #investor #stockmarket #stocks #stock #stockmarketnews

Proactive’s Tylah Tully breaks down ‘Just the Facts’ of the latest news from Lindian Resources Ltd (ASX:LIN, OTC:LINIF). The company continues to advance development at the Kangankunde Rare Earths Project in Malawi. Lindian has secured a US$50 million non-binding term sheet with Gerald Group for funding and offtake, with due diligence and technical reviews underway to finalise binding terms. Workshops and a site visit are planned later this month, with progress on track within the funding exclusivity period. The processing flowsheet has been optimised for greater cost efficiency and technical robustness, with final designs pending. A diamond drilling program completed in November has provided key samples for metallurgical testing and marketing discussions. The design and contract process for plant construction is nearing finalisation, with an award expected in the coming weeks, subject to funding. A new site office has been completed and regulatory approvals for a site access road are secured, with contracts for its construction in progress. Lindian has outlined an 18-month plan targeting production by mid-2026 and Stage 2 expansion studies by late 2025. A CFO recruitment process is underway to support funding and governance. An investor webinar, scheduled for January 22, 2025, will provide updates on the project and introduce the newly appointed non-executive chair. #LindianResources #RareEarths #KangankundeProject #MiningDevelopment #ProjectFunding #GeraldGroup #MetallurgicalTesting #DandCContract #RareEarthIndustry #SustainableMining #MalawiMining #SiteDevelopment #ProcessingPlant #InvestorWebinar #US50MillionFunding #MiningNews #RareEarthElements #Stage2Expansion #OptimisedFlowsheet #MiningUpdates

Proactive’s Tylah Tully breaks down ‘Just the Facts’ of the latest news from Australian Vanadium Ltd (ASX:AVL, OTCQB:ATVVF). The company has secured Western Australia Environmental Protection Agency (EPA) approval for the Gabanintha Vanadium Project. This project, part of the larger Australian Vanadium Project in the Mid-West region, includes plans for an open-cut mine, concentrator and a processing plant at nearby Tenindewa. Western Australia’s Minister for Environment Reece Whitby has endorsed the proposal, which also involves key infrastructure such as a bore field and camp. The company is advancing an Optimised Feasibility Study to integrate the Gabanintha Project into its broader operations to enhance project economics. The project aims to produce vanadium concentrate for export and high-purity vanadium oxides, supporting Australia's transition to a net zero economy. Australian Vanadium CEO Graham Arvidson described the EPA approval as a significant milestone towards construction and production, reinforcing confidence in obtaining remaining approvals. The company expressed gratitude to the Western Australian Government for its support and reaffirmed its commitment to fostering positive relationships with community stakeholders. #AustralianVanadium #MiningApproval #GabaninthaProject #VanadiumProduction #EPAApproval #WesternAustralia #VanadiumOxide #NetZeroEconomy #VanadiumIndustry #FutureMadeInAustralia #SustainableMining #MiningNews #MidWestWA #MineralProcessing #RenewableEnergySupport #VanadiumMarket #GeraldtonPort #ResourceDevelopment #FeasibilityStudy #EnvironmentApproval

Proactive’s Tylah Tully breaks down ‘Just the Facts’ of the latest news from Peninsula Energy Ltd (ASX:PEN, OTCQB:PENMF). The company has has updated stakeholders on its Lance ISR Uranium Project in Wyoming, USA, following its December 18, 2024, restart. The project has run efficiently, capturing 1,100 pounds of uranium in the ion exchange system by year-end. The company is focused on ramping up wellfield operations and production flow rates. Construction of Phase II plant facilities, including resin elution and uranium precipitation circuits, is progressing, with completion expected this month. Installation of the first yellowcake dryer unit is underway, with initial production targeted for March 2025. State approval has been received to expand the mine permit area to include the Kendrick Project area, though additional permits are needed before commencing uranium recovery operations. While the Kendrick area is pivotal to Peninsula’s 10-year production plan, no operations are planned there in 2025. Peninsula ended 2024 with an unaudited cash balance of US$45 million, providing the resources to finalise Phase II construction and ramp up production from Mine Unit 3, the first unit to utilise low pH leaching. A conference call for investors, hosted by CEO Wayne Heili, is scheduled for January 16, 2025, to discuss operations and 2025 priorities. #PeninsulaEnergy #UraniumProduction #ISRMining #LanceProject #WyomingMining #NuclearEnergy #YellowcakeProduction #LowpHLeaching #EnergyTransition #MineralProcessing #MiningUpdate #KendrickProject #UraniumIndustry #CleanEnergySolutions #ResourceExpansion #MiningOperations #InvestorUpdate #PhaseIIRampUp #EnvironmentalApprovals #UraniumMarket

Livium Ltd (ASX:LIT, OTC:LMMFF) managing director and CEO Simon Linge talked with Proactive’s Tylah Tully about the company's progress with its proprietary LieNA® technology. A partnership with Mineral Resources (MinRes) to progress the lithium extraction technology focusing on the commercialisation of this innovation has taken a significant step forward with further activities to optimise the process. Linge discussed how the two companies have been working under their joint development agreement signed in August 2023. He highlighted the successful completion of engineering studies and pilot programs, which demonstrated the technology's potential for producing high-quality lithium phosphate. He stated, “We might be able to scale the technology in a different way that gets us to a commercial outcome sooner.” Looking ahead, Livium plans to conduct further optimisation work over the next nine months, aiming to produce battery-grade lithium carbonate and accelerate the commercialisation pathway. Linge emphasised that the company remained fully funded for this phase, thanks to efficient budget management and support from MinRes. The continued development of LieNA® positions Livium to advance its goal of transforming the lithium production landscape. More updates are expected in the latter half of the year. #LiviumLtd #LieNATechnology #LithiumExtraction #BatteryGradeLithium #MineralResources #LithiumCarbonate #LithiumInnovation #SustainableEnergy #ProactiveInvestors #EnergyTechnology

Voyageur Pharmaceuticals CEO Brent Willis joined Steve Darling from Proactive to announce the commencement of human testing for the company's latest suite of barium contrast products, designed to optimize radiographic examinations of the gastrointestinal tract. The product lineup, including SmoothX, SmoothHD, SmoothLD, VisionHD, and VisionLD, is tailored to provide enhanced clarity, detail, and versatility for both adult and pediatric imaging applications. Willis emphasized the importance of this milestone, as it represents a critical step toward the company's goal of entering the Canadian market in 2025. The human testing process is being conducted in two phase with Phase 1 in Q1 2025 and will focus on assessing product performance based on key indicators such as imaging quality, diagnostic yield, contrast administration success rates, detection sensitivity, and patient safety. The company says some additional metrics will include patient satisfaction, procedure completion rates, adverse event rates, and compliance rates will also be closely monitored. These advanced formulations are designed to meet diverse clinical needs, ensuring high performance while maintaining safety and ease of use for patients. Voyageur aims to set a new standard in barium contrast agents, offering both precision and reliability in diagnostic imaging. This testing phase is an essential step in achieving regulatory approval and market readiness. #proactiveinvestors #voyageurpharmaceuticalsltd #tsxv #vm #vyyrf #ctscan #xray #BrentWillis, #RainCage, #Nanoscience, #MRI, #CTScan, #MedicalBreakthrough, #Fullerenes, #Vanadium, #Gadolinium, #Bismuth, #Iodine, #Radiology, #MedicalInnovation, #DrugDevelopment, #Healthcare, #ScientificBreakthrough,

Hillcrest Energy Technologies CEO Don Currie joined Steve Darling from Proactive to share significant updates on the company’s strategic initiatives, marking a new phase in its evolution. These initiatives underscore the maturation of Hillcrest's proprietary Zero Voltage Switching (ZVS) technology and an expanded focus on application-specific development and accelerated commercialization. Key to this transition is the appointment of Nad Karim as Vice President of Business Development. Karim brings over 20 years of experience in launching and scaling technology-driven businesses, with expertise in electric vehicle batteries, semiconductor IP, and advanced manufacturing technologies. His leadership is expected to drive Hillcrest’s efforts to bring its groundbreaking ZVS technology to market. Currie highlighted the company's strategic shift from technology development to commercialization, including streamlining operations and designating specialized Centers of Excellence: The Vancouver Lab will be dedicated to advancing power conversion technologies for grid applications, including renewable energy integration, energy storage, and data centers. The German Automotive Center of Excellence will focus on accelerating the adoption of ZVS technology in electric vehicles. The team has expanded its automotive offerings by incorporating FPGA-based control systems, complementing the existing microcontroller technology. These strategic moves aim to enhance Hillcrest's capabilities in critical market segments, positioning the company to deliver scalable, industry-specific solutions. The streamlined approach and expanded expertise highlight Hillcrest’s readiness to drive commercialization and support the energy transition. #proactiveinvestors #hillcrestenergytechnologiesltd #cse #heat #ptcqb #hlrtf

C3 Metals CEO Dan Symons joined Steve Darling from Proactive to unveil promising results from the company’s surface mapping and rock sampling program at its Khaleesi copper-gold project in Southern Peru. The project, located on the world-class Andahuaylas-Yauri Porphyry-Skarn belt, continues to deliver significant mineralization, showcasing the project's potential as an untapped resource. Recent rock chip samples from the mapping and sampling program revealed grades of up to 1.80% copper, 4.4 g/t gold, and 403 ppm molybdenum, further expanding the previously identified skarn, porphyry, and epithermal vein copper-gold mineralization. Symons emphasized the strategic importance of the Khaleesi project, which covers a 30,000-hectare concession package and lies within 45 km of major copper operations such as the Las Bambas (MMG) and Constancia (Hudbay Minerals) mines. In addition to sampling, the company has launched a comprehensive 50-metre grid soil sampling program across the project area. To deepen the understanding of Khaleesi’s subsurface potential, C3 Metals is undertaking multiple geophysical surveys, including a 45.5-line kilometre ground magnetic survey, a 24.5-line kilometre Induced Polarization (IP) survey, and a MT/AMT survey, all scheduled for completion by Q1 2025. The data from these advanced exploration efforts will be instrumental in designing Khaleesi’s maiden drill program, a key milestone as the company seeks to unlock the full potential of this promising copper-gold deposit. With its strategic location on a world-class mineral belt and ongoing positive results, Khaleesi is positioned to become a major asset in C3 Metals' portfolio. #proactiveinvestors #c3metalsinc #tsxv #cccm #otcqb #cuauf #CopperExploration #GoldMining #KhaleesiProject #PeruMining #ResourceInvesting #MiningUpdates

Eco Atlantic Oil & Gas Ltd chief executive Gil Holzman talked with Proactive's Stephen Gunnion about the company’s strategic moves and plans for 2025. Holzman explained a key development—the completion of a $12 million equivalent share buyback through a swap with Africa Oil, reducing the share count by 16%. He emphasised that this enhances shareholder value by increasing each shareholder’s stake in the company’s assets. Holzman highlighted Eco Atlantic's portfolio of eight exploration licenses across Namibia, South Africa, and Guyana. He noted that the licenses include some of the hottest oil and gas exploration areas globally. Significant plans for 2025 include potential farm-out deals, drilling activities, and advancing partnerships with industry leaders such as TotalEnergies and QatarEnergy. Additionally, Holzman announced the appointment of Emily Ferguson, a seasoned professional with 22 years of experience, to Eco Atlantic's board of directors. Ferguson’s extensive background in exploration and geoscience, including her work with TotalEnergies, is expected to be a valuable asset to the company. Eco Atlantic is gearing up for an active year, with plans in motion across its global licenses. Holzman thanked Africa Oil for its collaboration and emphasised the impact of the reduced share count on the company’s future activities and shareholder returns. Visit Proactive's YouTube channel for more videos, and don’t forget to give the video a like, subscribe to the channel, and enable notifications for updates! #EcoAtlantic #OilAndGas #EnergyExploration #GilHolzman #AfricaOil #NamibiaExploration #SouthAfricaDrilling #GuyanaOil #EnergyInvesting #2025EnergyTrends

Roquefort Therapeutics PLC (LSE:ROQ, OTCQB:ROQAF) CEO Ajan Reginald discussed the company’s proposed sale of subsidiary Lyramid to Pleiades Pharma with Proactive's Stephen Gunnion. Reginald explained that the sale, valued at a minimum of $10 million in cash and equity, marks the first step in Roquefort’s transformational strategy for 2025. He described it as a significant return on investment, as the company initially acquired Lyramid for £1 million in 2021. Pleiades Pharma, led by Caroline Fortier, has a strong track record of successful exits, amounting to $750 million in the past decade. Reginald highlighted that the deal also validates Roquefort’s value creation model and underscores its current market undervaluation. The sale represents one and a half times Roquefort’s market capitalisation, showcasing the company’s ability to acquire, develop, and monetise high-value assets. "We believe the upside potential with Pleiades Pharma is significant," Reginald stated, noting Pleiades' focus on building and exiting clinical asset portfolios. He also hinted at further opportunities, with two other assets in Roquefort’s portfolio already advancing toward value creation. Stay tuned to Proactive’s channel for updates on this exciting deal, and don’t forget to give the video a like, subscribe, and enable notifications for future content. #RoquefortTherapeutics #PharmaDeals #ClinicalAssets #LyramidSale #PleiadesPharma #BiotechInvestments #AssetSale #Biopharma #AjanReginald #ProactiveUpdates