Katie’s One-On-One with Zohran Mamdani

In this special live episode recorded during Colorectal Cancer Awareness Month, she sits down with Kevin Conroy, CEO of Exact Sciences and the force behind Cologuard; Judy Faulkner, founder and CEO of Epic Systems; and epidemiologist Dr. Caitlin Murphy to dig into why this disease keeps striking younger people. They cover the leading theories like ultra-processed foods, microplastics, the microbiome and debate whether the screening age should drop below 45, and get into the symptoms doctors too often brush off. If you know someone in their 30s or 40s, send them this one. It could save a life.See omnystudio.com/listener for privacy information.

Colorectal cancer is one of the few cancers that can often be prevented through screening, yet far too many people aren’t getting screened on time. In this episode of Medically Speaking, Dr. Eve Glazier welcomes back the show’s very first guest, award-winning journalist Katie Couric, for an ongoing conversation and call to action for Colorectal Cancer Awareness Month. Joined by Fola May, MD, PhD, UCLA gastroenterologist, and researcher, they discuss what’s changed in the conversation around colorectal cancer, why screening matters more than ever, the symptoms people should never ignore, and how to choose among today’s screening options. They also explore the barriers that keep people from follow-through — and why turning awareness into action can save lives. Find Dr. Glazier online at: https://www.uclahealth.org/medicallyspeakinghttps://www.instagram.com/uclahealthmedicallyspeakinghttps://www.tiktok.com/@uclamedicallyspeaking https://www.instagram.com/dreveglazierSee omnystudio.com/listener for privacy information.

California Governor Gavin Newsom has spent his career outrunning a public image that reduces him to a caricature—slick, ambitious, and impossibly polished. But in this wide-ranging conversation, recorded in-person in Los Angeles, Newsom explains why his new memoir, A Young Man in a Hurry, is an earnest attempt to show people the person behind the persona. (So far, most reviews agree that it is.) Now a leading Democratic voice taking on Donald Trump, Newsom describes his approach (in short: “punch that bully in the face”) and wrestles with how his record in California will play on the national stage—offering a revealing look at his vision for the US in the coming years.See omnystudio.com/listener for privacy information.

Longevity is having a moment far beyond Silicon Valley, and as we all look not just to live longer but to live better, In this episode of Next Question, Katie sits down with longevity researcher Dr. Rhonda Patrick.What the science makes clear is that aging isn’t a simple cause-and-effect story. Genetics do matter, but they are only part of the picture and research shows it may be a smaller part then we think. How quickly your body declines — and what you do to combat disease and promote healthy cells along the way — plays a much bigger role.The conversation covers why exercise is the closest thing we have to a longevity drug, why heart health impacts everything from mobility to brain function, and how supporting blood flow and oxygen delivery can make a meaningful difference as we age.See omnystudio.com/listener for privacy information.

In this special live episode of Next Question with Katie Couric, Katie talks with Best Actress nominee (and true multi-hyphenate), Kate Hudson about her role in the new movie, Song Sung Blue. Twenty-five years after her last Oscar nomination, Kate talks about why people think this is her best role yet, the importance of taking risks in your 40s, and what it is about the film that is resonating with so many people. And don’t worry–They also dish on kissing Hugh Jackman.See omnystudio.com/listener for privacy information.

As Americans grapple with a sharp rise in political violence, controversial immigration enforcement, and a growing sense of institutional breakdown, Pennsylvania Governor Josh Shapiro joins Katie for a conversation about power, accountability, and the future of the Democratic Party. Shapiro discusses the crisis in Minneapolis, the erosion of trust between communities and law enforcement, and the constitutional stakes of federal intervention. He also opens up about the personal trauma that shaped his new book, Where We Keep the Light—and makes the case for leadership rooted in empathy, restraint, and a renewed commitment to democratic values.See omnystudio.com/listener for privacy information.

If you only listen to one thing to make sense of the news this year… make it this. The final episode of this season of Next Question pulls together the most important conversations of the year. You’ll hear David Graham on Project 2025, Liz Oyer on the plethora of presidential pardons, Tina Brown on the year’s biggest scandals here at home and across the pond. Plus, many more. It’s a crash course in the last twelve months, how we made it through the year, and a look at what might be coming in 2026.See omnystudio.com/listener for privacy information.

Katie turns to veteran New York Times correspondent David Sanger to help make sense of a whirlwind few weeks in national security. Sanger explains why President Trump is using the U.S. military in ways he’s never seen in the five presidencies he’s covered—from sinking more than 20 boats in the Caribbean to deploying the National Guard in cities without clear emergencies. Katie presses him on the unanswered questions around those strikes, including a reported second hit on a burning boat and why the administration won’t release basic information.They also dig into the leaked Russia-Ukraine peace plan and the questions raised about how closely it aligns with Kremlin preferences. And as they discuss the tragic killing of the National Guard member in D.C., Sanger makes the case for why America still owes its Afghan allies protection—now more than ever.See omnystudio.com/listener for privacy information.

In this special live episode of Next Question with Katie Couric, recorded at the 92nd Street Y, New York, Katie sits down with beauty icon Bobbi Brown to talk about her new memoir Still Bobbi: A Masterclass in Leading an Authentic Life. The two longtime friends share stories from Bobbi’s trailblazing career — from Bobbi’s guest appearances as a regular contributor on the Today Show to the creation of Bobbi Brown Cosmetics and her new beauty venture, Jones Road. With humor and heart, they dig into what it means to stay true to yourself, build resilience, and reinvent at any age.See omnystudio.com/listener for privacy information.

CAR T therapy has delivered remarkable results for people with certain blood cancers—sometimes sending aggressive disease into deep remission after a single infusion. But today, only about 20% of eligible patients can actually get it. In this episode, sponsored by our partners at Allogene Therapeutics, Katie sits down with Dr. Zachary Roberts to unpack why access remains so limited and how new allogeneic (or “off-the-shelf”) CAR T therapies could be a turning point. They discuss how using healthy donor T-cells, rather than a patient’s own, may help bypass manufacturing hurdles and bring advanced treatment to more oncologists, more hospitals, and more communities. To learn more, visit Alpha3trial.com. #AllogenePartnerSee omnystudio.com/listener for privacy information.