This episode unpacks the updated BCLC guidelines for hepatocellular carcinoma management. Experts discuss the strengths and limitations of the BCLC model in an era of rapidly evolving systemic therapies and personalised care, sharing real-world examples of when the algorithm helps and when clinical practice diverges.Host: Mattias MandorferSpeakers:  Marco Sanduzzi, Lorenza RimassaThis episode is also available on EASL Campus: https://easlcampus.eu/tltm/episode-05

As deaths from advanced chronic liver disease rise, many patients never receive timely palliative care.In this episode, we explore why early, holistic support is essential in advanced liver disease and HCC, and unpack key recommendations from the new EASL Position Paper to help reduce suffering and improve quality of life.Host:  Debbie Shawcross Speakers: Patrizia-Künzler-Heule, Sumita Verma This episode is also available on EASL Campus: https://easlcampus.eu/tltm/episode-04

This episode explores whether MetALD is a meaningful clinical entity or an unnecessary complication. Experts discuss the overlap between metabolic dysfunction and alcohol use, the challenges of applying the MetALD definition in practice, and its impact on classification, guidelines, drug development, and patient care. Host:  Thomas Marjot Speakers:  Mary Rinella ,  Aleksander Krag This episode is also available on EASL Campus: https://easlcampus.eu/tltm/episode-03

EASL’s Secretary General and Vice Secretary General share an open conversation on the challenges and opportunities for women in hepatology. The episode explores the role of mentorship across career stages and reflects on the journey toward EASL’s first female Secretary General, offering insights on leadership and change in the field.Host: Maja ThieleSpeakers: Debbie Shawcross, Ana LleoThis episode is also available on EASL Campus: https://easlcampus.eu/tltm/episode-02

In collaboration with the Indian National Association for the Study of the Liver (INASL), hepatologists from South Asia and North America/Europe take listeners inside their liver wards to explore how regional context shapes acute liver care. From admission patterns to alcohol use, infections, DILI, nutrition, and access to transplant, the episode highlights key differences and opportunities for shared learning across regions.This episode is also available on EASL Campus: https://easlcampus.eu/tltm/episode-01

This EASL Studio episode brings key insights from the 2025 EASL–AASLD Consensus Conference on Primary Biliary Cholangitis (PBC).Experts explore the use of surrogate endpoints, the challenges in current trial design and regulation, the value of real-world evidence, and how quality-of-life assessment can support future pathways.Moderator: David JonesSpeakers: Marco Carbone, Bettina Hansen, and Ana LleoAll EASL Studio Podcasts are available on EASL Campus.Click here to see all EASL Video Podcasts on Apple Podcasts.

How can we protect young adults from steatotic liver disease (SLD)? This episode explores the burden of MASLD, MetALD, and ALD in Europe, the synergistic effects of alcohol and metabolic risk factors, and why the younger population is especially vulnerable. Experts also examine the disparities in risk factors and the role of clinics and policymakers in prevention.Moderator: Shira Zelber SagiSpeakers: Carina Ferreira-Borges (WHO representative) and Zobair YounossiThis EASL Studio is supported by Opella. EASL has received no input from Opella with regards to the content of this programme.All EASL Studio Podcasts are available on EASL Campus.Click here to see all EASL Video Podcasts on Apple Podcasts.

What were the key takeaways from this year’s AASLD The Liver Meeting? In this episode, experts unpack the most impactful studies, clinical insights, and emerging trends shaping the future of hepatology. From liver cancer breakthroughs to MASLD, ALD, and beyond.Moderator: Debbie ShawcrossSpeakers: Saul Karpen, Allison Kwong, Mazen NoureddinAll EASL Studio Podcasts are available on EASL Campus.Click here to see all EASL Video Podcasts on Apple Podcasts.

For World Antimicrobial Awareness Week 2025 (“Act Now: Protect Our Present, Secure Our Future”), this EASL Studio explores the balance between rifaximin’s benefits in hepatic encephalopathy and the global challenge of antimicrobial resistance.Moderator: Debbie ShawcrossSpeakers: Rajiv Jalan, Vishal Patel, Jonel TrebickaAll EASL Studio Podcasts are available on EASL Campus.Click here to see all EASL Video Podcasts on Apple Podcasts.This EASL Studio is supported by Alfasigma and Norgine. EASL has received no input from Alfasigma or Norgine with regards to the content of this programme.

Ever wondered what happens to your manuscript after submission? In this episode, the JHEP Reports editorial team takes you behind the scenes: from first triage to reviewer selection, smart moves vs. red flags, and how final decisions are made. The discussion also explores the potential, limitations, and ethical pitfalls.Moderator: Mattias Mandorfer Speakers: Tobias Böttler, Virginia Hernández-Gea, Josep LlovetAll EASL Studio Podcasts are available on EASL Campus.Click here to see all EASL Video Podcasts on Apple Podcasts.