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16:46
While there are more treatments now than ever before for neuromuscular diseases like muscular dystrophy, patients who have very specific gene mutations associated with these diseases have few options. Dr. Elizabeth McNally says a discovery in her lab could lead to a new therapy for muscular dystrophy, including its rare forms.
Flere episoder fra "Breakthroughs"
Human Genome Project for Proteins with Neil Kelleher, PhD
18:04
Millions of molecular proteins are swimming through our body's cells and many studies have discovered that these proteins are the main drivers of all human diseases. Scientists are now mapping proteins the way the Human Genome Project mapped genes. Northwestern's Neil Kelleher is at the forefront of the Human Proteoform Project and explains how it could lead to more targeted and effective diagnostics and treatments for diseases.Reversing Severe Spinal Cord Injuries with Samuel Stupp, PhD
20:29
Regenerative nanomedicine is being used to develop new therapies for devastating conditions such as severe spinal cord injuries. Northwestern's Dr. Samuel Stupp is a pioneer in the field of regenerative nanomedicine and recently published a paper in the journal Science that details how a new injectable therapy uses synthetic nanofibers to reverse severe spinal cord injuries in animals and how this therapy could soon be used in humans.Gå ikke glip af nogen episoder af “Breakthroughs” - abonnér på podcasten med gratisapp GetPodcast.
Earliest Signs of Parkinson's Disease with D. James Surmeier, PhD
34:27
Northwestern Medicine scientists have discovered one of the earliest signs of Parkinson's disease, proving that damaged neuronal mitochondria alone can cause symptoms of the disease, according to a study published in Nature. Senior author D. James Surmeier, chair of the Feinberg department of Neuroscience, who has over 30 years of experience in the field, explains the importance of these findings for future Parkinson's research and therapeutics.The Northwestern Medicine African American Transplant Access Program with Dinee Simpson, MD
24:24
People who are Black make up the largest group of minorities in need of an organ transplant. In 2019, Northwestern Medicine launched the African American Transplant Access Program to help address this problem. Founding director of the program Dinee Simpson, MD, talks about the barriers to organ transplant for Black patients and how she is working to bring down those barriers in Chicago with innovative outreach, community-engaged research and more.Variants of Interest and of Concern with Judd Hultquist, PhD
22:32
This spring, the World Health Organization began using the Greek alphabet to label key variants of SARS-CoV-2. The Greek names make it easier to talk about variants with the public, but in the scientific community these variants are being discussed and studied at the molecular level to learn as much as possible about their evolution, replication and mutation. Judd Hultquist, PhD, shares insight on SARS-CoV-2 variants. He is an assistant professor of Medicine in the Division of Infectious Diseases at Feinberg and an HIV scientist whose lab has shifted many resources to study SARS-CoV-2, to track the origin of its variants and also understand how antiviral proteins found in humans can protect against COVID-19 and other viruses.Advancing Muscular Dystrophy Research with Elizabeth McNally, MD, PhD
16:46
While there are more treatments now than ever before for neuromuscular diseases like muscular dystrophy, patients who have very specific gene mutations associated with these diseases have few options. Dr. Elizabeth McNally says a discovery in her lab could lead to a new therapy for muscular dystrophy, including its rare forms.Next-Generation COVID Vaccines with Pablo Penaloza-MacMaster, PhD
19:28
As the Delta variant of SARS-CoV-2 is causing breakthrough infections in some vaccinated people around the world, scientists at Northwestern Medicine are developing and studying potential next-generation COVID-19 vaccines that could be more effective at preventing and clearing breakthrough infections. Pablo Penaloza-MacMaster, assistant professor of Microbiology-Immunology at Feinberg, discusses recent studies from his lab that aim to improve current COVID-19 vaccines.The Evolution of Cardiac Monitoring with Rod Passman, MD
14:18
As heart conditions like arrhythmia become increasingly common, heart monitoring is becoming an even more important tool for disease prevention and treatment. Northwestern Medicine cardiac electrophysiologist Rod Passman, MD, who has over three decades of experience in the field, reviews the history of cardiac monitoring and looks to the future. He details his pioneering use of implantable heart monitors for arrhythmia in stroke patients and his partnership with a consumer electronics company to bring wearable cardiac monitors to patients.Esophageal Diseases and Symptom Anxiety and Hypervigilance with John Pandolfino, MD
15:26
Esophageal diseases are extremely common, and symptoms such as trouble swallowing, chest pain, regurgitation and choking diminish quality of life. There can also be psychosocial effects for patients with these diseases that includes hypervigilance — a heightened focus on physical symptoms — and symptom-specific anxiety such as fear of choking. Identifying patients with issues could help providers better treat their disease. That's according to a new Northwestern Medicine study published in the journal Gastroenterology.Kids, Mental Health and COVID-19 with Tali Raviv, PhD
18:21
A recent survey of more than 32,000 caregivers of Chicago Public School students found that around a quarter children and adolescents were described as stressed, anxious, angry or agitated in the months after remote learning began. Black and Latinx participants experienced significantly more of these stressors. Dr. Tali Raviv, associate professor of Psychiatry and Behavioral Sciences at Feinberg explains the results and offers insight.
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