Preconception Supplements for Gene SNPs

Doing a good detox protocol takes some preparation and some of the best preparation you can do is finding out if your genes are making detoxification harder for you somewhere. Some gene SNPs have the potential to make detox harder by interfering with phase two conjugation reactions. These include MTHFR, MTR, MTRR, GST, GPX, COMT, HNMT, UGT1A1, SULT genes, NAT1, and NAT2. With each category of gene SNP, I will also give suggestions for improving that aspect of your phase two detoxification reactions. 00:00 - Intro 00:49 - Why SNPs matter and how to test 02:08 - Genes that affect methylation and how to help 02:46 - Genes that affect glutathione and how to help 03:38 - Genes that affect sulfation and how to help 04:20 - Genes that affect glucuronidation and how to help 05:52 - Genetic Rockstars walkthrough 07:42 - Genes that affect acetylation and how to help 08:11 - Amino acid conjugation GENETIC ROCKSTARS (an MTHFR community): community.tohealthwiththat.com FREE COURSE: MTHFR Basics: https://to-health-with-that.teachable.com/p/mthfr-basics WORK WITH DR. AMY ONE-ON-ONE: Set up a free meet and greet appointment to see if we’re a good fit to work together, or if group coaching, community, or something else might be a better option: https://calendly.com/amy-tohealthwiththat/15min GROUP COACHING: https://www.tohealthwiththat.com/group-coaching/ WEBSITE: https://tohealthwiththat.com/ AFFILIATE LINKS: I appreciate you using these links to purchase products you would buy anyway, because they allow me to keep putting information out there. Thank you! SEEKING HEALTH (methylation and histamine support supplements - these ship internationally): https://bit.ly/3afXYH4 STRATEGENE REPORT (detailed genetics using 23andme or ancestry raw data): https://bit.ly/3retbm5 FULLSCRIPT (professional grade supplements): https://us.fullscript.com/welcome/thwt QUEEN OF THE THRONE (castor oil and castor oil packs):  https://shop.queenofthethrones.com/amy-tohealthwiththat use code AMY_TOHEALTHWITHTHAT10 for 10% off of any order of $59 or more --- Send in a voice message: https://podcasters.spotify.com/pod/show/tohealthwiththat/message

Detox is amazing for your body, so why does it feel so awful? The great news is that symptoms of detoxification may be helpful in giving your signals about what is happening. We'll quickly review phases I - III of detoxification, why things can feel bad, where detoxification gets stuck, and how to plan for an easier detoxification. 00:00 - Intro 00:58 - 3 phases of detox 02:54 - detox uses energy and resources 04:24 - Four reasons why detox feels bad 06:31 - Plan ahead for easier detox 07:21 - Symptoms of detox GENETIC ROCKSTARS (an MTHFR community): community.tohealthwiththat.com FREE COURSE: MTHFR Basics: https://to-health-with-that.teachable.com/p/mthfr-basics WORK WITH DR. AMY ONE-ON-ONE: Set up a free meet and greet appointment to see if we’re a good fit to work together, or if group coaching, community, or something else might be a better option: https://calendly.com/amy-tohealthwiththat/15min GROUP COACHING: https://www.tohealthwiththat.com/group-coaching/ WEBSITE: https://tohealthwiththat.com/ AFFILIATE LINKS: I appreciate you using these links to purchase products you would buy anyway, because they allow me to keep putting information out there. Thank you! SEEKING HEALTH (methylation and histamine support supplements - these ship internationally): https://bit.ly/3afXYH4 STRATEGENE REPORT (detailed genetics using 23andme or ancestry raw data): https://bit.ly/3retbm5 FULLSCRIPT (professional grade supplements): https://us.fullscript.com/welcome/thwt QUEEN OF THE THRONE (castor oil and castor oil packs):  https://shop.queenofthethrones.com/amy-tohealthwiththat use code AMY_TOHEALTHWITHTHAT10 for 10% off of any order of $59 or more --- Send in a voice message: https://podcasters.spotify.com/pod/show/tohealthwiththat/message

In the last episode, we discussed the fact that toxins come from food, air, water, personal care products, and pretty much everything we encounter. Detoxification is an ongoing process that is always at work in your body. Here are the basics about how detoxification happens, what resources your body needs, and why it sometimes feels yucky. Detoxification happens in three phases. Phase one involves chemical reactions, mostly in the cytochrome P450 system. Phase two comprises conjugation reactions so that substances can be transported out of the tissues, and phase three is the active transport of these toxins out of your tissues and into waste material. 00:00 - intro 00:29 - Why Detox is easy to get wrong 01:19 - Three phases of detoxification 01:40 - Detoxification Phase one and cytochrome P450 system 02:31 - Genetic Rockstars quick walk-through 04:36 - Detoxification Phase two, conjugation reactions, and gene SNPS 05:15 - Phase three reactions and toxin transport 05:43 - You have to eliminate to detox 06:26 - Water and detox 06:50 - Limit toxin exposure 08:05 - Detox uses energy and nutrients 09:01 - Practitioner support and detox kits GENETIC ROCKSTARS (an MTHFR community): community.tohealthwiththat.com FREE COURSE: MTHFR Basics: https://courses.tohealthwiththat.com/p/mthfr-basics WORK WITH DR. AMY ONE-ON-ONE: Set up a free meet and greet appointment to see if we’re a good fit to work together, or if group coaching, community, or something else might be a better option: https://calendly.com/amy-tohealthwiththat/15min GROUP COACHING: https://www.tohealthwiththat.com/group-coaching/ WEBSITE: https://tohealthwiththat.com/ AFFILIATE LINKS: I appreciate you using these links to purchase products you would buy anyway, because they allow me to keep putting information out there. Thank you! SEEKING HEALTH (metylation and histamine support supplements - these ship internationally): https://bit.ly/3afXYH4 STRATEGENE REPORT (detailed genetics using 23andme or ancestry raw data): https://bit.ly/3retbm5 FULLSCRIPT (professional grade supplements): https://us.fullscript.com/welcome/thwt QUEEN OF THE THRONE (castor oil and castor oil packs):  https://shop.queenofthethrones.com/amy-tohealthwiththat use code AMY_TOHEALTHWITHTHAT10 for 10% off of any order of $59 or more --- Send in a voice message: https://podcasters.spotify.com/pod/show/tohealthwiththat/message

Toxins are everywhere in modern life, and they have always been a normal part of life because they come from food, bacteria, mold, yeast, air, water, and the soil. Also, now, industrial and agricultural chemicals, the products we use on our skin, teeth, hair, and nails, and things we use to care for our homes like air fresheners, cleaning products, and that sort of thing. Toxins are everywhere and they can accumulate in your system causing symptoms like fatigue, exhaustion, brain fog, weakness, poor memory, difficulty concentrating, skin outbreaks, constipation, and irritability. Let's talk about where toxins come from and how toxins make you feel, and this will start our short mini-series on detoxifying. 00:00 - Intro 00:35 - Where toxins come from 01:24 - Detox is always happening 02:06 - Why toxins cause fatigue 02:48 - Toxicity is a vague term 03:39 - General toxic symptoms 04:00 - Voluntary toxins 04:42 - Drugs and supplements 06:36 - Surgical toxins 07:05 - Toxins and genes 08:20 - Cytochrome P-450 09:11 - What is coming up in the toxin mini-series GENETIC ROCKSTARS (an MTHFR community): https://community.tohealthwiththat.com FREE COURSE: MTHFR Basics: https://courses.tohealthwiththat.com/p/mthfr-basics WORK WITH DR. AMY ONE-ON-ONE: Set up a free meet and greet appointment to see if we’re a good fit to work together or if group coaching, community, or something else might be a better option: https://calendly.com/amy-tohealthwiththat/15min GROUP COACHING: https://www.tohealthwiththat.com/group-coaching/ WEBSITE: https://tohealthwiththat.com/ AFFILIATE LINKS: I appreciate you using these links to purchase products you would buy anyway, because they allow me to keep putting information out there. Thank you! SEEKING HEALTH (methylation and histamine support supplements - these ship internationally): https://bit.ly/3afXYH4 STRATEGENE REPORT (detailed genetics using 23andme or ancestry raw data): https://bit.ly/3retbm5 FULLSCRIPT (professional grade supplements): https://us.fullscript.com/welcome/thwt QUEEN OF THE THRONE (castor oil and castor oil packs):  https://shop.queenofthethrones.com/amy-tohealthwiththat use code AMY_TOHEALTHWITHTHAT10 for 10% off of any order of $59 or more --- Send in a voice message: https://podcasters.spotify.com/pod/show/tohealthwiththat/message

Problems with oxygenation can affect your sleep quality and quantity, leaving you feeling tired, or like you slept but woke up as tired as you were the night before, or just plain exhausted. Iron deficiency and carbon monoxide poisoning are both oxygen problems, not that we think of them that way, but many oxygen problems are more subtle. The classic oxygen problem overnight is sleep apnea, which causes you to wake up through the night becuase you stop breathing momentarily. Mouth breathing at night also impairs oxygen and leads to fatigue, low energy, and a poor night's sleep. My favorite solution to this problem is mouth taping. 00:00 - Intro 00:40 - Iron deficiency and carbon monoxide poisoning 01:55 - Sleep Apnea 02:21- Types of Sleep Apnea 03:08 - Sleep apnea treatment 03:36 - Sinuses and fatigue 04:07 - Mouth breathing and fatigue 05:15 - Why mouth breathing causes fatigue 05:45 - Three differences between breathing through your nose and mouth 07:05 - Fix mouth breathing with mouth taping GENETIC ROCKSTARS (an MTHFR community): community.tohealthwiththat.com FREE COURSE: MTHFR Basics: https://courses.tohealthwiththat.com/p/mthfr-basics WORK WITH DR. AMY ONE-ON-ONE: Set up a free meet and greet appointment to see if we’re a good fit to work together, or if group coaching, community, or something else might be a better option: https://calendly.com/amy-tohealthwiththat/15min GROUP COACHING: https://www.tohealthwiththat.com/group-coaching/ WEBSITE: https://tohealthwiththat.com/ AFFILIATE LINKS: I appreciate you using these links to purchase products you would buy anyway, because they allow me to keep putting information out there. Thank you! SEEKING HEALTH (metylation and histamine support supplements - these ship internationally): https://bit.ly/3afXYH4 STRATEGENE REPORT (detailed genetics using 23andme or ancestry raw data): https://bit.ly/3retbm5 FULLSCRIPT (professional grade supplements): https://us.fullscript.com/welcome/thwt QUEEN OF THE THRONE (castor oil and castor oil packs):  https://shop.queenofthethrones.com/amy-tohealthwiththat use code AMY_TOHEALTHWITHTHAT10 for 10% off of any order of $59 or more --- Send in a voice message: https://podcasters.spotify.com/pod/show/tohealthwiththat/message

Sex hormones have a lot to do with how energetic you feel, or how sleepy, or how grumpy. So, let's talk about how estrogen ties into sleep, weight, and metabolism. How progesterone helps insomnia and gets stolen by stress hormones. Also, how testosterone is a feel-good chemical. We'll also talk about xenoestrogens, which come from outside your body, and how to reduce estrogen, boost progesterone and testosterone, and generally find hormone balance. 00:00 - intro 00:29 - What sex hormones do 00:59 - Estrogen and metabolism 01:40 - Estrogen dominance 02:03 - Xenoestrogens (estrogen from chemicals) 02:25 - Two ways to manage estrogen levels 02:30 - Avoid estrogen from chemicals 03:43 - Detoxify estrogen better 03:53 - Estrogen detox needs good methylation 05:00 - Progesterone, sleep, and stress 06:25 - Testosterone and wellbeing 07:04 - High estrogen causes low testosterone 07:48 - Men need weight bearing exercise 08:02 - Losing weight leads to estrogen spikes 08:20 - Supplements for Testosterone 08:38 - Energy changes in menstrual cycle 09:26 - The bottom line GENETIC ROCKSTARS (an MTHFR community): community.tohealthwiththat.com FREE COURSE: MTHFR Basics: https://courses.tohealthwiththat.com/p/mthfr-basics WORK WITH DR. AMY ONE-ON-ONE: Set up a free meet and greet appointment to see if we’re a good fit to work together, or if group coaching, community, or something else might be a better option: https://calendly.com/amy-tohealthwiththat/15min GROUP COACHING: https://www.tohealthwiththat.com/group-coaching/ WEBSITE: https://tohealthwiththat.com/ AFFILIATE LINKS: I get a small profit when you choose to buy from these links, so thank you! SEEKING HEALTH (methylation and histamine support supplements - these ship internationally): https://bit.ly/3afXYH4 STRATEGENE REPORT (detailed genetics using 23andme or ancestry raw data): https://bit.ly/3retbm5 FULLSCRIPT (professional grade supplements): https://us.fullscript.com/welcome/thwt QUEEN OF THE THRONE (castor oil and castor oil packs):  https://shop.queenofthethrones.com/amy-tohealthwiththat use code AMY_TOHEALTHWITHTHAT10 for 10% off of any order of $59 or more --- Send in a voice message: https://podcasters.spotify.com/pod/show/tohealthwiththat/message

There is nothing more frustrating than waking up in the middle of the night and not being able to go back to sleep easily. Nighttime waking is draining and exhausting, and you wake up feeling like you might as well not have bothered with all of those hours of tossing and turning. So, what can you do to help you sleep through the night without waking up? Let's talk about some options. 00:00 - Intro 01:13 - Time release melatonin 02:23 - Night-time blood sugar spikes 02:35 - Dawn Phenomenon 03:08 - Night waking with "normal" blood sugars 03:31 - Diet changes for blood sugar overnight 04:05 - Supplements for overnight blood sugar 05:00 - Prescription changes for nighttime waking in diabetes 05:19 - Night-time cortisol spikes 06:23 - Supplement to manage overnight cortisol 07:07 - Histamine spikes at night 07:46 - Supplements to lower histamine at night 08:18 - Hormones and insomnia 09:04 - Supplements to help preserve progesterone --- Send in a voice message: https://podcasters.spotify.com/pod/show/tohealthwiththat/message

Supplements to help you fall asleep are a big topic, and there are many to choose from, but these are my favorite supplements to get you to sleep faster. GENETIC ROCKSTARS (an MTHFR community): community.tohealthwiththat.com FREE COURSE: MTHFR Basics: https://courses.tohealthwiththat.com/p/mthfr-basics WORK WITH DR. AMY ONE-ON-ONE: Set up a free meet and greet appointment to see if we’re a good fit to work together, or if group coaching, community, or something else might be a better option: https://calendly.com/amy-tohealthwiththat/15min GROUP COACHING: go.tohealthwiththat.com/watch-the-free-videoWEBSITE: https://tohealthwiththat.com/ AFFILIATE LINKS: I get a small profit when you choose to buy from these links, so thank you! SEEKING HEALTH (methylation and histamine support supplements - these ship internationally): https://bit.ly/3afXYH4 STRATEGENE REPORT (detailed genetics using 23andme or ancestry raw data): https://bit.ly/3retbm5 FULLSCRIPT (professional grade supplements): https://us.fullscript.com/welcome/thwt QUEEN OF THE THRONE (castor oil and castor oil packs):  https://shop.queenofthethrones.com/amy-tohealthwiththat use code AMY_TOHEALTHWITHTHAT10 for 10% off of any order of $59 or more 00:00 - Intro 00:49 - Make sure you're not taking something that keeps you awake 01:13 - Special precaution with MTHFR 01:57 - Body won't relax 02:28 - Magnesium 03:15 - Opposite reaction to magnesium 03:30 - GABA 03:57 - Passionflower 04:15 - Agitated mind 04:34 - Valerian Root 04:58 - Bifidobacterium longum 1714 05:42 - Aromatherapy 06:23 - Chamomile 06:58 - Glycine 07:25 - Melatonin 09:18 - Next episode --- Send in a voice message: https://podcasters.spotify.com/pod/show/tohealthwiththat/message

MTHFR gene mutations can create a lot of havoc in your life if they aren't properly managed and sleep disorders are just one of the many problems. This video will talk about the most impactful morning and evening sleep routines for MTHFR and also give some tips for the best diet to support great sleep in a person wtih the MTHFR gene mutation. GENETIC ROCKSTARS (an MTHFR community): community.tohealthwiththat.com FREE COURSE: MTHFR Basics: https://courses.tohealthwiththat.com/p/mthfr-basics WORK WITH DR. AMY ONE-ON-ONE: Set up a free meet and greet appointment to see if we’re a good fit to work together, or if group coaching, community, or something else might be a better option: https://calendly.com/amy-tohealthwiththat/15min GROUP COACHING: mmm.tohealthwiththat.com WEBSITE: https://tohealthwiththat.com/ AFFILIATE LINKS: I get a small profit when you choose to buy from these links, so thank you! SEEKING HEALTH (metylation and histamine support supplements - these ship internationally): https://bit.ly/3afXYH4 STRATEGENE REPORT (detailed genetics using 23andme or ancestry raw data): https://bit.ly/3retbm5 FULLSCRIPT (professional grade supplements): https://us.fullscript.com/welcome/thwt QUEEN OF THE THRONE (castor oil and castor oil packs):  https://shop.queenofthethrones.com/amy-tohealthwiththat use code AMY_TOHEALTHWITHTHAT10 for 10% off of any order of $59 or more Chapters: 00:00 - Intro 00:35 - Methylation and sleep 01:00 - Mental factors in sleep problems with MTHFR 01:18 - Physical contributors to sleep problems with MTHFR 01:38 - Right folate plus right methyl donors 02:17 - How to find your perfect doses 03:09 - Synthetic folic acid and sleep 03:40 - Blood sugars and sleep 04:25 - Best bedtime routine for great sleep with MTHFR 07:16 - Best morning routine to help sleep with MTHFR 08:12 - Activities to include in your day for great sleep with MTHFR If you know or suspect you have MTHFR or a methylation issue, be sure to subscribe to the podcast for health tips, MTHFR hacks and great information. --- Send in a voice message: https://podcasters.spotify.com/pod/show/tohealthwiththat/message

Sleep anxiety is the horror circle that lies at the intersection of insomnia and anxiety disorders that createes a torturous loop in which a person is worried they won't sleep, and the anxiety ironically prevents them from sleeping. Nightmare. Here's the link to the breaking mental bad habits video: https://youtu.be/5rpKe_hsk3Y?si=8IgE1AlhjsqiPtjx 00:00 - Intro 00:30 - What is sleep anxiety 01:19 - How sleep anxiety arises 02:09 - Origins of sleep anxiety 03:04 - Sleep disorders and medication changes 03:44 - Ritualized sleep routine 04:56 - Vigorous exercise 05:37 - Ignoring sleep completely 06:48 - Cognitive Behavioral Therapy -Insomnia 07:45 - Prescription medications 08:29 - Breaking mental bad habits --- Send in a voice message: https://podcasters.spotify.com/pod/show/tohealthwiththat/message