Introducing What’s Up Docs? With Chris and Xand van Tulleken

In their new BBC Radio 4 podcast, Drs Chris and Xand are on a mission to help us take better care of ourselves.

What's the science behind a sweet tooth? James Gallagher explores whether sugar really can be addicted and what happens in our bodies when we want it and when we eat it. He's joined by Professor Susanne Dickson, who specialises in the neurobiology of appetite at the University of Gothenburg, and Professor James Brown from the School of Biosciences at Aston University.With Easter coming up, James meets dental hygienist and researcher Dr Claire McCarthy from King's College London in the BBC loos to get some top tips on keeping our teeth clean and gets a few pointers on where he could do with brushing up on his technique. Presenter: James Gallagher Producers: Tom Bonnett and Hannah Robins Assistant Producer: Anna Charalambou

We continue our exploration of some of the issues that could crop up if assisted dying becomes law under The Terminally Ill Adults (End of Life) Bill that is currently working its way through Parliament.Today we consider what those final moments might be like and if the ideal of a peaceful death is a reality with the drug options currently available.To discuss we're joined by:Katherine Sleeman - Professor of Palliative Care at King's College London David Nicholl - Consultant Neurologist at University Hospital Birmingham Mark Taubert - Consultant Palliative Medicine at NHS Wales Erica Borgstrom - Professor of Medical Anthropology at The Open UniversityIt's claimed that within each of us there is a credit card's worth of microplastics. We dig into the figures underlying that with Kit Yates, Professor of Mathematical Biology at the University of Bath.And, we answer your questions after our programme on hearing loss with audiologist Dr Hannah Cooper, Kevin Munro, Professor of Audiology at the University of Manchester and Nish Mehta, an Ear, Nose and Throat surgeon at Royal National ENT Hospital.Presenter: James Gallagher Producers: Hannah Robins and Tom Bonnett Editor: Holly Squire

You sent in your questions on dementia and now we're tackling them. Professor Tara Spires-Jones, Director of the Centre for Discovery Brain Sciences at the University of Edinburgh, joins James Gallagher to go through the [email protected] mailbag.James also visits mushroom grower the Bristol Fungarium which has teamed up with the University of the West of England to examine a mushroom called lion's mane.Lion's mane has a lot of hype about it online as well as a long history in traditional medicine and neuroscientist Dr Tim Craig and his team are taking it into their to lab to investigate whether it might harbour properties that could benefit people with dementia.Thanks to everyone who sent in questions after listening to our episode 'What next for Alzheimer's treatment' which is available on BBC Sounds: https://www.bbc.co.uk/programmes/m0024ng7 Presenter: James Gallagher Producer: Tom Bonnett Editor: Holly Squire

We continue our exploration of some of the issues that could crop up if assisted dying becomes law under The Terminally Ill Adults End of Life Bill that is currently working its way through Parliament.Today we tackle safeguarding. How can we be certain an assisted death is what the person wants? And who should even bring up the conversation?To discuss we're joined by:Katherine Sleeman - Professor of Palliative Care at King's College London David Nicholl - Consultant Neurologist at University Hospital Birmingham Mark Taubert - Consultant Palliative Medicine at NHS Wales Erica Borgstrom - Professor of Medical Anthropology at The Open UniversityPresenter: James Gallahgher Producers: Hannah Robins Assistant Production: Tom Bonnett and Siobhan

The Terminally Ill Adults End of Life Bill is working its way through Parliament. If it became law in England and Wales it would be one of those moments in history that profoundly changes society. There are similar discussions taking place in Scotland, the Isle of Man and Jersey too. To be clear about what we’re doing on Inside Health. We’re not going to debate the rights or wrongs of assisted dying. Or go through the politics of the Bill. Instead, over the next few episodes we’re going to explore some of the issues that will come up if assisted dying goes ahead. We’re going to start with eligibility and who could get an assisted death under the proposed rules? To discuss we're joined by:Katherine Sleeman - Professor of Palliative Care at King's College London David Nicholl - Consultant Neurologist at University Hospital Birmingham Mark Taubert - Consultant Palliative Medicine at NHS Wales Erica Borgstrom - Professor of Medical Anthropology at The Open UniversityAlso in the programme we have exclusive research on the differences between men and women’s immune systems and why that affects the risks of infection and even autoimmune disease. James speaks Professor Lucy Wedderburn from the Great Ormond Street Institute of Child Health and Director of the Centre for Adolescent Rheumatology at University College London, and Associate Professor Dr Lizzy Rosser also from the Centre for Adolescent Rheumatology at University College London.Presenter: James Gallagher Producers: Hannah Robins & Tom Bonnett

Five years on from the first Covid lockdown in the UK, we consider how the pandemic changed medicine. We're joined by Dr Emma Wall, academic consultant in Infectious Diseases at University College London Hospital who also runs a long covid clinic, Professor Katrina Pollock, Associate Professor in Vaccinology at the Oxford Vaccine Group and Jon Otter Director for Infection Prevention and Control at Guy’s Hospital London. Presenter: James Gallagher Producer: Hannah Robins

John is registered blind, and relies on his hearing to get around in his everyday life. But as he has got older, he’s started to notice his hearing deteriorate. He wants to know – is there anything available in between the initial solution of wax removal, and the final destination of hearing aids? He emailed Inside Health to ask James Gallagher to investigate. James speaks to Nish Mehta, an Ear, Nose and Throat surgeon at Royal National ENT Hospital, to find out how we hear, and learn about the different causes of hearing loss. He then visits UCL Ear Institute to undergo a hearing test with audiologist Dr Hannah Cooper, and see the potential future of hearing tests with Professor Maria Chait, an auditory cognitive neuroscientist. But hearing in day to day life is not as simple as in a science laboratory. James meets Kevin Munro, Professor of Audiology at the University of Manchester, in a noisy café to discuss hearing aid technologies and learn about their latest advancements. Presenter: James Gallagher Producer: Hannah Fisher Editor: Holly Squire and Colin Paterson

Fitness trackers at the ready! Join James Gallagher at Cardiff Science Festival as he runs through the ways wearable tech is making an impact on health and how it might shape the future of medicines and care. With him are Dr Sanne Lugthart, Haematology consultant at the University Hospital of Bristol and Weston NHS Foundation Trust. She's pioneering using wearables and an app to track pain in people who suffer from sickle cell disease. Also on the panel is Professor Kathryn Peall who is Personal Chair, Division of Psychological Medicine and Clinical Neurosciences at Cardiff University. Kathryn tells James all about working with data from the UK Biobank to test if wearables could predict Parkinson's disease. She's also developing 80s-style headbands that could help take hospital grade sleep monitoring to the comfort of the bedroom. And, running experiments with the audience and on his skydiving assistant Danni, James is also joined by Damian Bailey, Professor of Physiology and Biochemistry from the University of South Wales.Presenter: James Gallagher Producers: Tom Bonnett and Hannah Robins Production Co-ordinator: Ishmael Soriano Editor: Colin Paterson

When we hit our teens it's often a time when everything starts to change. We meet new friends through work or studies, we start going out more at night and we're often in new situations independent from our parents. For people with severe allergies it can be a risky time because they have all this change in their life, on top of what Priya Matharu calls the 'full time job' of managing your condition. Presenter James Gallagher talks to Priya about her experience of having severe allergies from a young age and how she has coped with reactions that mean just touching her face after chopping a carrot has put her in hospital. For Priya, when she reached adolescence and moved out of her family it was a scary time and she had to grow up quickly to take responsibility for her allergies. In a recent debate in the House of Lords it was discussed that moving young people out of the paediatric allergy services they have grown up with the support of and into adult services, just as everything else in their life is changing too can be really difficult for patients, and potentially dangerous. Dr Claudia Gore from Imperial College Healthcare NHS Trust shared her experience of working in a children's allergy clinic in London for that debate and she joins James along with Dr Paul Turner from Imperial College London to discuss how this transition from children's to adult services could be made safer and smoother for patients.Also in the programme, James is joined again by Dr Vanessa Apea, Consultant in Genito-Urinary and HIV medicine at Barts Health NHS Trust to answer more of your questions on genital herpes, UTIs and urinary incontinence.Presenter; James Gallagher Producer: Tom Bonnett Assistant Producer: Anna Charalambou Editor: Colin Paterson