AudioScholar Ophthalmology Weekly

Editor's Pick: Three-Year Outcomes of Trabeculotomy vs Combined Trabeculotomy-Trabeculectomy for Primary Congenital Glaucoma (Ophthalmology, 2026) This AudioScholar briefing is generated by artificial intelligence for healthcare professionals and trainees. It is not medical advice. Welcome to This Week in Ophthalmology. This week we're covering 10 notable papers spanning glaucoma from the nursery to the screening clinic, the safety and prognosis of retinal injections and surgery, and drug-related and HLA-B27 ocular inflammation… This week's papers: 1. Three-Year Outcomes of Trabeculotomy vs Combined Trabeculotomy-Trabeculectomy for Primary Congenital Glaucoma.. Ophthalmology 2026. 2. Baseline Macular OCT Thickness of Ocular Hypertensive Patients Improves Prediction of Glaucoma.. American Journal of Ophthalmology 2026. 3. Defining the optimal duration of remote home tonometry for accurate characterization of intraocular pressure fluctuation.. Ophthalmology 2026. 4. External validation of a deep-learning algorithm for perimetric glaucoma detection on color fundus photographs in the Rotterdam Study.. Ophthalmology 2026. 5. Endophthalmitis risk after intravitreal anti-vascular endothelial growth factor injection using prefilled versus vial-drawn syringes: An agent-specific systema…. Survey of Ophthalmology 2026. 6. Combined Versus Monotherapy Anti-Complement and Anti-Vascular Endothelial Growth Factor Intravitreal Injections for Age-Related Macular Degeneration: Safety Ou…. Ophthalmology Retina 2026. 7. Post-Pars Plana Vitrectomy Endophthalmitis in Patients with and without Systemic Immunosuppression.. Retina 2026. 8. Fluid fluctuation and visual outcomes in neovascular age-related macular degeneration: A systematic review and meta-analysis.. Survey of Ophthalmology 2026. 9. Short-term Risk of Inflammatory Eye Reactions Following Bisphosphonate Use: A nationwide case-case-time-control study.. Ophthalmology 2026. 10. Correlation of initial treatment with time to resolution of HLA-B27-associated acute anterior uveitis.. American Journal of Ophthalmology 2026. Listen at https://audioscholar.cc/episode/gyfs8engay

Editor's Pick: Time Course of Resolution of Diabetic Macular Edema by Sustained Suppression of VEGF-A with the Port Delivery Platform with Ranibizumab (American Journal of Ophthalmology, 2026) This AudioScholar briefing is generated by artificial intelligence for healthcare professionals and trainees. It is not medical advice. Welcome to This Week in Ophthalmology. This week we're covering 10 notable papers spanning anti-VEGF therapy and its limits in the macula, pediatric eye care from screening through surgery, and the reliability of diagnostic signals and donor tissue i… This week's papers: 1. Time Course of Resolution of Diabetic Macular Edema by Sustained Suppression of VEGF-A with the Port Delivery Platform with Ranibizumab.. American Journal of Ophthalmology 2026. 2. AI-Based OCT Assessment of Anatomic Response During the Loading Phase of Anti-VEGF Therapy in Neovascular Age-Related Macular Degeneration.. Investigative Ophthalmology and Visual Science 2026. 3. Submacular Hemorrhage Requiring Procedural Intervention During Anti-VEGF Therapy for Neovascular Age-Related Macular Degeneration in Japan: The JTY Three-Cente…. Retina 2026. 4. Validation of the TWO-ROP Algorithm in the Shenzhen Prematurity Eye Study.. Ophthalmology Retina 2026. 5. Risk-Stratified Outcomes of Prophylactic Laser Versus Observation for Pediatric Peripheral Retinal Lesions.. Ophthalmology Retina 2026. 6. Pediatric Endothelial Keratoplasty: A Modified Delphi Consensus by the EKLG Study Group on Indications, Surgical Techniques, and Postoperative Care.. American Journal of Ophthalmology 2026. 7. Diagnostic Accuracy of Paracentral Acute Middle Maculopathy for Arteritic Anterior Ischemic Optic Neuropathy.. American Journal of Ophthalmology 2026. 8. False-Positive Acanthamoeba Keratitis From Multiplex Polymerase Chain Reaction Diagnostics, a Case Series.. Cornea 2026. 9. Corneal Transplantation From Donors With a Documented History of Suspected Sepsis: Infectious Risks and Graft Outcomes.. Cornea 2026. 10. Autologous Anterior Lens Capsule as an Intrascleral Spacer in Deep Sclerectomy: A Randomized Clinical Trial.. American Journal of Ophthalmology 2026. Listen at https://audioscholar.cc/episode/zmhchzzr9e

Editor's Pick: Incidence and Risk Factors of Recurrent Visual Field Progression in Glaucoma (JAMA Ophthalmology, 2026) This AudioScholar briefing is generated by artificial intelligence for healthcare professionals and trainees. It is not medical advice. Welcome to This Week in Ophthalmology. This week we're covering 10 notable papers spanning glaucoma risk stratification, imaging biomarkers that forecast disease in the retina and beyond, and treatment of difficult anterior and posterior segment cond… This week's papers: 1. Incidence and Risk Factors of Recurrent Visual Field Progression in Glaucoma.. JAMA Ophthalmology 2026. 2. Association Between Systemic TNF-α Inhibitor Use and Risk of Primary Open-Angle Glaucoma.. American Journal of Ophthalmology 2026. 3. Longitudinal analysis of structural biomarkers for disease progression in intermediate age-related macular degeneration: a MACUSTAR study report.. Ophthalmology Retina 2026. 4. Risk Factors for Retinal Pigment Epithelium Tears in Patients with Neovascular Age-Related Macular Degeneration: A Systematic Review and Meta-Analysis.. American Journal of Ophthalmology 2026. 5. OCT to Assess Risk of Progression of Multiple Sclerosis: A Report by the American Academy of Ophthalmology.. Ophthalmology 2026. 6. Systematic Review of Clinical Utility of Multimodal Imaging in Infectious Posterior Uveitis. Multimodal imaging in Uveitis (MUV) Taskforce Report 12.. Ophthalmology Retina 2026. 7. Artificial intelligence in diabetic retinopathy: From deep learning to foundation models, clinical translation, and real-world deployment.. Survey of Ophthalmology 2026. 8. Efficacy of Oral Belzutifan for Retinal Capillary Hemangioblastomas in von Hippel-Lindau Disease.. Ophthalmology Retina 2026. 9. Supervised Reduction Protocol for Management of Herpetic Stromal Keratitis.. Cornea 2026. 10. Morgagnian Cataract: Clinical Features, Surgical Management, and Outcomes.. American Journal of Ophthalmology 2026. Listen at https://audioscholar.cc/episode/d4cxrwkx62

Editor's Pick: Artificial intelligence-supported diabetic retinopathy screening in Tanzania: a randomised controlled trial (The Lancet Global Health, 2026) This AudioScholar briefing is generated by artificial intelligence for healthcare professionals and trainees. It is not medical advice. Welcome to This Week in Ophthalmology. This week we're covering 10 notable papers spanning diabetic eye disease and screening, vitreoretinal surgery and its complications, ocular oncology, and the ocular surface. Let's dive in. This week's papers: 1. Artificial intelligence-supported diabetic retinopathy screening in Tanzania: a randomised controlled trial.. The Lancet Global Health 2026. 2. Serum Ang-1, sFLT-1, and sST2 Profiles Distinguish Anti-VEGF Responders in Diabetic Macular Edema.. Retina 2026. 3. Outcomes of Complex Retinal Detachment Repair with Proliferative Vitreoretinopathy Grade C using the Cincinnati Methotrexate Protocol.. Ophthalmology Retina 2026. 4. Pharmacological strategies for the prevention and treatment of proliferative vitreoretinopathy: A comprehensive review.. Survey of Ophthalmology 2026. 5. Clinical outcomes of epiretinal membrane surgery in patients with good baseline visual acuity.. Retina 2026. 6. Aspergillus Endophthalmitis: Clinical Features, Treatment Modalities, and Visual Outcomes.. Investigative Ophthalmology and Visual Science 2026. 7. Cytopathology and Prognostic Accuracy of 15-GEP/PRAME: The Collaborative Ocular Oncology Group Study 2.. JAMA Ophthalmology 2026. 8. The Second and Third Decade After 103Pd Plaque Brachytherapy for Choroidal Melanoma.. Ophthalmology 2026. 9. Topical Insulin in the Treatment of Ocular Surface Disease: A Retrospective Cohort Study.. Cornea 2026. 10. Severe Dupilumab-Associated Ocular Surface Disease: Multicenter Experience and Management Considerations.. Cornea 2026. Listen at https://audioscholar.cc/episode/jbpqynngr8

Editor's Pick: Diabetes Severity in Cornea Donors and 1-Year Outcomes in Recipients in the Diabetes Endothelial Keratoplasty Study: A Secondary Analysis of a Randomized Clinical Trial (JAMA Ophthalmology, 2026) This AudioScholar briefing is generated by artificial intelligence for healthcare professionals and trainees. It is not medical advice. Welcome to This Week in Ophthalmology. This week we're covering 10 notable papers spanning retinal disease from gene-based vision restoration to real-world anti-VEGF care, anterior segment and glaucoma surgery, and infection control and care delivery… This week's papers: 1. Optogenetic Therapy for Restoring Aspects of Visual Function.. New England Journal of Medicine 2026. 2. Management of Neovascular Age-Related Macular Degeneration in Routine US Clinical Practice: Impact of Delayed Treatment Initiation.. Ophthalmology Retina 2026. 3. Pooled Data Meta-Analysis of Pneumatic Vitreolysis for Treatment of Vitreomacular Traction Syndrome With, And Without Full Thickness Macular Holes.. Retina 2026. 4. Incidence of Retinal Artery Occlusion After Carotid Endarterectomy Versus Carotid Artery Stenting.. Retina 2026. 5. Diabetes Severity in Cornea Donors and 1-Year Outcomes in Recipients in the Diabetes Endothelial Keratoplasty Study: A Secondary Analysis of a Randomized Clini…. JAMA Ophthalmology 2026. 6. Surgical Management Patterns and Outcomes in Recurrent Corneal Erosion: An IRIS Registry Study.. Cornea 2026. 7. Mitomycin C Application during Trabeculectomy-Injection versus Sponge: A Report by the American Academy of Ophthalmology.. Ophthalmology 2026. 8. Endphthalmitis after cataract surgery in Sweden 2018-2024: associations with preoperative visual acuity and intracameral antibiotic regimens.. British Journal of Ophthalmology 2026. 9. Assessment of the Necessity for High-Level Disinfection (HLD) of Reusable Ophthalmic Devices: A Multisociety Position Paper.. Ophthalmology 2026. 10. Diagnostic Accuracy and Clinical Impact of Ocular Fundus Imaging in the Emergency Department: A Systematic Review and Meta-Analysis.. Survey of Ophthalmology 2026. Listen at https://audioscholar.cc/episode/qw3e4s69e9

Editor's Pick: Paracentral acute middle maculopathy in giant cell arteritis versus non-arteritic anterior ischaemic optic neuropathy (British Journal of Ophthalmology, 2026) This AudioScholar briefing is generated by artificial intelligence for healthcare professionals and trainees. It is not medical advice. Welcome to This Week in Ophthalmology. This week we're covering 10 notable papers spanning glaucoma monitoring and surgery, the retina from macular degeneration to diabetic vitrectomy, and the inflammatory and ischaemic disease that sits between opht… This week's papers: 1. In-office and remote intraocular pressure metrics associated with visual field progression in treated open-angle glaucoma.. Ophthalmology 2026. 2. Central visual field defect patterns and progression in glaucoma: a multicentre 10-year study.. British Journal of Ophthalmology 2026. 3. Influence of goniotomy incisional arc size on its efficacy and safety in juvenile open-angle glaucoma: a prospective multicentre study.. British Journal of Ophthalmology 2026. 4. Cholesteryl Ester Transfer Protein Inhibition and Risk of Age-Related Macular Degeneration.. Ophthalmology 2026. 5. From Intermediate AMD to Geographic Atrophy: Biomarkers, Endpoints, and a Roadmap for Next-Generation Clinical Trials.. Progress in Retinal and Eye Research 2026. 6. Artificial intelligence for clinical decision-making in retinal disorders: From screening and diagnosis to treatment and longitudinal management.. Progress in Retinal and Eye Research 2026. 7. Anti-Vascular Endothelial Growth Factor Injection-to-Surgery Interval in Diabetic Vitrectomy: A Systematic Review and Meta-Analysis.. Ophthalmology Retina 2026. 8. Association Between Extrafoveal Paravascular Retinoschisis and Central Retinal Vessel Trunk Dragging in High Myopia.. Investigative Ophthalmology and Visual Science 2026. 9. Paracentral acute middle maculopathy in giant cell arteritis versus non-arteritic anterior ischaemic optic neuropathy.. British Journal of Ophthalmology 2026. 10. Teprotumumab for Thyroid Eye Disease: A Systematic Review and Meta-Analysis of Randomized Controlled Trials and Real-World Studies.. American Journal of Ophthalmology 2026. Listen at https://audioscholar.cc/episode/2eafs2x5ka

Editor's Pick: Prevention of Retinal Detachment in Type 2 Stickler Syndrome (Ophthalmology, 2026) This AudioScholar briefing is generated by artificial intelligence for healthcare professionals and trainees. It is not medical advice. Welcome to This Week in Ophthalmology. This week we're covering 10 notable papers spanning prevention of blinding retinal disease in children and inherited syndromes, the medical retina evidence base for vein occlusion and diabetic retinopathy, corne… This week's papers: 1. Prevention of Retinal Detachment in Type 2 Stickler Syndrome.. Ophthalmology 2026. 2. Retinopathy of Prematurity in the Anti-VEGF Era: Screening Systems and Practical Treatment Decision-Making Across Anti-VEGF, Laser, and Surgery.. Progress in Retinal and Eye Research 2026. 3. Efficacy and safety of intravitreal conbercept injection in treating macular oedema secondary to branch retinal vein occlusion: results from the BRAVE study.. British Journal of Ophthalmology 2026. 4. Effect of systemic fibrates on diabetic retinopathy prevention and progression: A comprehensive systematic review and meta-analysis.. Survey of Ophthalmology 2026. 5. Incidence of De Novo Glaucoma and Ocular Hypertension After DMEK vs DSAEK: A Systematic Review and Meta-Analysis.. American Journal of Ophthalmology 2026. 6. Managing refractory herpes simplex keratitis.. British Journal of Ophthalmology 2026. 7. Incidence and characteristics of teprotumumab-associated ototoxicity in thyroid eye disease: A systematic review and meta-analysis.. Survey of Ophthalmology 2026. 8. Prevalence, Ocular Manifestations, and Treatment Response in Post-Bariatric Vitamin A Deficiency: A Systematic Review and Meta-Analysis.. American Journal of Ophthalmology 2026. 9. Conjunctival Melanocytic Lesions: A Practical Sequential Treatment Approach.. Ophthalmology 2026. 10. Organism-Specific Clinical Features and Outcomes of Culture-Positive Endogenous Endophthalmitis: A Multicenter Cohort Study Over 12 Years.. American Journal of Ophthalmology 2026. Listen at https://audioscholar.cc/episode/crt4acqdmn

Editor's Pick: Acute Stroke Risk and Trends in Secondary Prevention after Retinal Artery Occlusion (Ophthalmology Retina, 2026) Welcome to This Week in Ophthalmology. This week we're covering 10 notable papers spanning vitreoretinal surgical decision-making, the systemic and diagnostic stakes of retinal disease, and prognostic markers in glaucoma and paediatric eye care. This week's papers: 1. Gas tamponade choice in low-to-moderate complexity primary rhegmatogenous retinal detachment: propensity-matched comparisons of SF6, C2F6 and C3F8.. British Journal of Ophthalmology 2026. 2. Gas Versus Air Tamponade in Surgery for Full-Thickness Macular Hole: A Systematic Review and Meta-analysis.. Ophthalmology Retina 2026. 3. Scleral Buckling in Primary Vitrectomy for Giant Retinal Tears: A Systematic Review and Meta-Analysis of Anatomical and Functional Outcomes.. Ophthalmology Retina 2026. 4. Acute Stroke Risk and Trends in Secondary Prevention after Retinal Artery Occlusion.. Ophthalmology Retina 2026. 5. Outcomes of As-Needed Aflibercept Treatment After Complete Regression in Polypoidal Choroidal Vasculopathy.. JAMA Ophthalmology 2026. 6. Ocular Toxoplasmosis Masquerading as Acute Retinal Necrosis and Cytomegalovirus Retinitis: A Systematic Review.. Ophthalmology Retina 2026. 7. Predictors of Vision Loss and Surgical Intervention in Stevens-Johnson Syndrome: A Multicenter Nationwide Cohort Study.. American Journal of Ophthalmology 2026. 8. Centralized Multidisciplinary Retinoblastoma Care Closes the Outcome Gap: Survival and Globe Salvage for 1000 Eyes from 601 Patients.. Ophthalmology 2026. 9. Reversal of optic disc cupping in primary congenital glaucoma: analysis of 1223 eyes.. British Journal of Ophthalmology 2026. 10. Photography-based Retinal Vasculometry and Visual Field Progression in Primary Open Angle Glaucoma.. American Journal of Ophthalmology 2026. Listen at https://audioscholar.cc/episode/x8vc5scegh

Editor's Pick: Efficacy and Safety of Satralizumab for Thyroid Eye Disease: Week 24 Results from the Phase 3 SatraGO-1 and SatraGO-2 Randomized Trials (Ophthalmology, 2026) Welcome to This Week in Ophthalmology. This week we're covering 10 notable papers spanning targeted immunotherapy for thyroid eye disease, medical and surgical retina — from complement inhibition to prophylactic laser — and a cluster of studies on oc… This week's papers: 1. Efficacy and Safety of Satralizumab for Thyroid Eye Disease: Week 24 Results from the Phase 3 SatraGO-1 and SatraGO-2 Randomized Trials.. Ophthalmology 2026. 2. Why Metrics Matter in Thyroid Eye Disease: An Innovate TED Initiative.. JAMA Ophthalmology 2026. 3. Two-Year Experience with Intravitreal Pegcetacoplan for the Treatment of Geographic Atrophy in Clinical Practice.. American Journal of Ophthalmology 2026. 4. Association of Common Anti-Inflammatory Medications with Reduced Risk of Vision-Threatening Diabetic Retinopathy in Type 2 Diabetes.. Ophthalmology 2026. 5. Prophylactic Retinopexy in Fellow Eyes After Contralateral Retinal Detachment: A Systematic Review and Meta-analysis.. Ophthalmology Retina 2026. 6. Macular Hole Surgery With ILM Flap, Viscoelastic, and Air Tamponade Without Positioning.. Retina 2026. 7. Myopic Traction Maculopathy: consensus from the Myopia Society for a new nomenclature.. Ophthalmology Retina 2026. 8. Incidence and Management of Ocular Hypertension Following the 0.18 mg Fluocinolone Acetonide Implant for Non-infectious Uveitis affecting the Posterior Segment.. Retina 2026. 9. Dupilumab-associated ocular surface disease in atopic dermatitis: a large prospective cohort study from the BioDay registry.. American Journal of Ophthalmology 2026. 10. Management strategies in endogenous fungal endophthalmitis: a multi-institutional retrospective cohort study.. British Journal of Ophthalmology 2026. Listen at https://audioscholar.cc/episode/7xf28fnyex

Editor's Pick: Systemic Vascular Risks After Retinal Artery and Vein Occlusions: A Large-Scale Real-World Analysis (Retina, 2026) Welcome to This Week in Ophthalmology. This week we're covering 10 notable papers spanning new drug therapies for retinal and refractive disease, systemic risk and drug safety questions that land in our clinics, and a set of studies on how we detect,… This week's papers: 1. Safety and Effects of Gildeuretinol Acetate on Retinal Atrophic Lesions in Stargardt Disease: The TEASE-1 Randomized Clinical Trial.. JAMA Ophthalmology 2026. 2. GLP1-RA Use and Risk of Non-arteritic Anterior Ischemic Optic Neuropathy in Patients with Type 2 Diabetes.. Ophthalmology Retina 2026. 3. Evaluation of globe-preserving therapies in unilateral cT2/cT3 retinoblastoma: a multicentre study of 1566 eyes.. British Journal of Ophthalmology 2026. 4. Changing Trends in the Microbiological spectrum and clinical presentation of Postcataract Endophthalmitis over a 23-year period.. American Journal of Ophthalmology 2026. 5. Systemic Vascular Risks After Retinal Artery and Vein Occlusions: A Large-Scale Real-World Analysis.. Retina 2026. 6. Evidence and Consensus Based Imaging Guidelines in Ocular Toxoplasmosis. Multimodal imaging in Uveitis (MUV) Taskforce Report 14.. Ophthalmology Retina 2026. 7. Real-World Applicability of Anti-VEGF Trial Criteria for Diabetic Macular Edema.. American Journal of Ophthalmology 2026. 8. Event-Based Progression Detection Among OCT, OCT Angiography, and Visual Field in Glaucoma.. JAMA Ophthalmology 2026. 9. LYNX-1: A Phase 3 Study of 0.75% Phentolamine Ophthalmic Solution in Subjects with Dim Light Vision Disturbances.. American Journal of Ophthalmology 2026. 10. Outcomes of the Sub400 Protocol and Contact Lens-Assisted Corneal Cross-Linking in Advanced Thin-Cornea Keratoconus: Clinical Efficacy and Long-Term Visual Sta…. Cornea 2025. Listen at https://audioscholar.cc/episode/25tkderdkf